Epidural clonidine used being an adjunct to area anesthetics has 3 unique mechanisms of action. Initially, the stimulation of alpha-2-receptors in the dorsal horn lessens soreness transmission. Secondly, clonidine could cause regional vasoconstriction that limits vascular elimination of area epidural anesthetics. Clonidine is distributed in breast milk; caution is https://www.proleviate.com/post/the-new-pain-killer-conolidine