There is a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to lower afferent pain transmission and create analgesia. As a result, prescription drugs like clonidine that goal alpha-2 receptors can affect the transmission of pain. Applies to clonidine: oral https://popew581xuq0.blog-eye.com/profile