This analyze will Assess the pharmacological activity of PF-06305591 in wholesome male volunteers by examining the results of two dose levels of PF-06305591 on chilly ache intensity evoked by retaining non-dominant hand into a h2o tub stored at two+/- levels. System for planning in vivo formulation：Acquire μL DMSO grasp liquid, https://timj654sck4.wikijournalist.com/user